Principal Secretary: Dr Simon M. Zwane
Under Secretary ( Technical): Mrs Lungile Shongwe
Under Secretary ( Administration) : Mr Simon Kunene
Director of Health Services: Dr Vusi Magagula
Deputy Director of Health Services (Clinical): Dr Velephi Okello
Deputy Director of Health Services (Public Health): Mrs Rejoice Nkambule
Legal Advisor: Mrs Zandile Dlamini
Chief Nursing Officer: Mrs Thembisile Khumalo
Deputy Chief Nursing Officer: Mrs Glory Msibi-Dlamini
Senior Health Administrator: Vacant
Principal Environmental Officer: Mr Edmund Dlamini
Principal Personnel Officer: Ms Thabsile Simelane
Acting Principal Planning Officer: Mr Sifiso Mamba
Financial Controller: Mr Mlungisi Dlamini
Senior Dental Officer: Vacant
Regional Health Administrators
Hhohho Region: Mr Mkhosi Khumalo
Manzini Region:Mr Mlondolozi Dlamini
Shiselweni Region:Mrs Thoko Ngubeni -Simelane
Lubombo Region:Mr William Shongwe